Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497637 | 0.83 | PDE10A (0.40) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12354513 | 0.79 | CA12 (0.66) | CA12CA9NPC1RAB9AALOX5AP | |
| SCHEMBL23971546 | 0.77 | MAPT (0.47) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL172248 | 0.75 | CYP19A1 (0.61) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29683444 | 0.75 | CA12 (0.55) | CA12CA9NPC1RAB9AALOX5AP | |
| SCHEMBL4814620 | 0.75 | CA12 (0.55) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29497624 | 0.74 | CA12 (0.33) | CA12CA9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30547369 | 0.74 | ALOX5AP (0.51) | NPC1RAB9AALOX5APSMN1; SMN2MEN1 | |
| SCHEMBL29043819 | 0.74 | ALOX5AP (0.37) | CA12CA9NPC1RAB9AALOX5AP | |
| SCHEMBL29497688 | 0.74 | ALOX5AP (0.37) | CA12CA9NPC1RAB9AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022092180-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE THEREOF | 日本農薬株式会社 | 2022-05-05 | — | — | WO | disclosed |