Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | PRCP | P42785 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399589 | 1.00 | KDM1A (0.67) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL11812754 | 0.83 | MEN1 (0.47) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL2364359 | 0.82 | PRCP (0.67) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL30973233 | 0.82 | PRCP (0.67) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL14677170 | 0.82 | PRCP (0.67) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL24724254 | 0.80 | KDM1A (0.67) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL19399588 | 0.80 | KDM1A (1.00) | KDM1APRCPDRD2DRD1 | |
| SCHEMBL7849270 | 0.80 | KMT2A (1.00) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL14646680 | 0.80 | KMT2A (1.00) | KDM1AMEN1KMT2APRCPGAA | |
| SCHEMBL13804033 | 0.80 | KMT2A (1.00) | KDM1AMEN1KMT2APRCPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195713-B | Method for synthesizing dihydroisoquinoline by catalyzing selective dehydrogenation of tetrahydroisoquinoline | 广东众源药业有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-114195713-A | Method for synthesizing dihydroisoquinoline by catalyzing selective dehydrogenation of tetrahydroisoquinoline | 西安石油大学 | 2022-03-18 | — | — | CN | disclosed |