Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 16/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.43 |
| ▸ | CDK9 | P50750 | 12/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.43 |
| ▸ | CDK2 | P24941 | 10/20 | 0.43 |
| ▸ | CDK7 | P50613 | 12/20 | 0.40 |
| ▸ | CCNH | P51946 | 12/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 9/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076269 | 0.83 | CCNK (0.48) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL21179054 | 0.75 | CCNK (0.55) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30006772 | 0.73 | AR (0.39) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL28817288 | 0.73 | AR (0.39) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22076298 | 0.71 | CCNK (0.63) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29850505 | 0.71 | CCNK (0.63) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL28817419 | 0.71 | CCNK (0.63) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL26696831 | 0.71 | RPS6KA5 (0.38) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30716225 | 0.71 | RPS6KA5 (0.38) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL21179174 | 0.71 | CCNK (0.49) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063212-A1 | PYRIMIDYL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 广州费米子科技有限责任公司 | 2022-03-31 | — | — | WO | disclosed |