Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006772 | 1.00 | AR (0.39) | ARSLC22A12IDH1F11CCNT1 | |
| SCHEMBL22076269 | 0.76 | CCNK (0.48) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29498456 | 0.73 | CCNK (0.43) | SLC22A12CCNT1CCNKCCNE1CDK2 | |
| SCHEMBL3907077 | 0.70 | AR (0.54) | ARSLC22A12KDM4EMEN1ALDH1A1 | |
| SCHEMBL16115890 | 0.69 | IDH1 (0.44) | ARSLC22A12IDH1F11KDM4E | |
| SCHEMBL950544 | 0.67 | AR (0.68) | ARSLC22A12 | |
| SCHEMBL26696831 | 0.66 | RPS6KA5 (0.38) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL30716225 | 0.66 | RPS6KA5 (0.38) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL21179174 | 0.64 | CCNK (0.49) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL20846199 | 0.63 | HTR6 (0.45) | CCNT1CCNKCCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907407-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 江苏先声药业有限公司 | 2022-08-16 | — | — | CN | disclosed |