Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.51 |
| ▸ | MTOR | P42345 | 6/20 | 0.51 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727236 | 1.00 | ALDH1A1 (0.57) | ALDH1A1PIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL848293 | 1.00 | ALDH1A1 (0.57) | ALDH1A1PIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL2372122 | 0.93 | ALDH1A1 (0.65) | ALDH1A1POLBGAASMN1; SMN2KMT2A | |
| SCHEMBL29498556 | 0.92 | ALDH1A1 (0.51) | ALDH1A1PIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL19989269 | 0.92 | ALDH1A1 (0.51) | ALDH1A1PIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL17205857 | 0.89 | ALDH1A1 (0.57) | ALDH1A1PIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL17205858 | 0.89 | ALDH1A1 (0.57) | ALDH1A1PIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL29498568 | 0.87 | ALDH1A1 (0.51) | ALDH1A1PIK3CDPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL19989386 | 0.87 | ALDH1A1 (0.51) | ALDH1A1PIK3CDPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL19989203 | 0.87 | ALDH1A1 (0.51) | ALDH1A1PIK3CDPIK3CBPIK3CGPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715629-B | Aza-indazole compounds for use in tendon and/or ligament injuries | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |