Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994872 | 1.00 | MAPK1 (0.46) | MAPK1SMN1; SMN2POLBTP53PKM | |
| SCHEMBL19994803 | 0.92 | KMT2A (0.43) | MAPK1SMN1; SMN2POLBTP53PKM | |
| SCHEMBL19989275 | 0.88 | MAPK1 (0.42) | MAPK1SMN1; SMN2POLBTP53PKM | |
| SCHEMBL29859217 | 0.88 | MAPK1 (0.42) | MAPK1SMN1; SMN2POLBTP53PKM | |
| SCHEMBL19989276 | 0.88 | MAPK1 (0.42) | MAPK1SMN1; SMN2POLBTP53PKM | |
| SCHEMBL19989453 | 0.85 | ALDH1A1 (0.56) | MAPK1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL29498503 | 0.85 | ALDH1A1 (0.56) | MAPK1SMN1; SMN2POLBHTTKDM4E | |
| SCHEMBL21407132 | 0.84 | KMT2A (0.49) | MAPK1SMN1; SMN2POLBTP53PKM | |
| SCHEMBL29498518 | 0.84 | KMT2A (0.49) | MAPK1SMN1; SMN2POLBTP53PKM | |
| SCHEMBL19995179 | 0.84 | KMT2A (0.49) | MAPK1SMN1; SMN2POLBTP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715629-B | Aza-indazole compounds for use in tendon and/or ligament injuries | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |