Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALPL | P05186 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498577 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TP53TDP1ALPLKMT2A | |
| SCHEMBL29498541 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TP53TDP1ALPLKMT2A | |
| SCHEMBL31368924 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TP53TDP1ALPLKMT2A | |
| SCHEMBL3448568 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TP53TDP1ALPLKMT2A | |
| SCHEMBL29498544 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TP53 | |
| SCHEMBL29498509 | 0.75 | PIK3CD (0.47) | ALDH1A1TP53TDP1EDNRAHTT | |
| SCHEMBL12464421 | 0.74 | ALDH1A1 (0.64) | ALDH1A1TP53TDP1ALPLKMT2A | |
| SCHEMBL29498593 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TP53TDP1ALPLKMT2A | |
| SCHEMBL29498617 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TP53TDP1EDNRAHTT | |
| SCHEMBL29498618 | 0.74 | PIK3CD (0.58) | ALDH1A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715629-B | Aza-indazole compounds for use in tendon and/or ligament injuries | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |