SCHEMBL29498781

CCCC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC

nearest known ligand 0.80

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	14/20	0.75

▸	GCGR	P47871	9/20	0.75

▸	GIPR	P48546	6/20	0.75

▸	CALCR	P30988	3/20	0.69

▸	KEAP1	Q14145	1/20	0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29536792	1.00	GLP1R (0.75)	GLP1RGCGRGIPRCALCRKEAP1
SCHEMBL31454131	0.97	GLP1R (0.76)	GLP1RGCGRGIPRCALCRKEAP1
Exenatide SCHEMBL28323280	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1
Exenatide SCHEMBL29827241	0.96	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1
SCHEMBL29576071	0.96	GLP1R (0.80)	GLP1RGCGRGIPRCALCR
SCHEMBL31072728	0.96	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1
SCHEMBL29429437	0.96	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1
SCHEMBL30473764	0.96	GLP1R (0.80)	GLP1RGCGRGIPRCALCR
Exenatide SCHEMBL20509814	0.96	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1
SCHEMBL30626174	0.96	GLP1R (0.78)	GLP1RGCGRGIPRCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-107735128-B	Drug delivery device with load indicator	赛诺菲	2022-04-12	—	—	CN	disclosed