Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327386 | 0.86 | SMN1; SMN2 (0.39) | ATMSIRT1MAOAMAOBMEN1 | |
| SCHEMBL24496706 | 0.86 | SMN1; SMN2 (0.39) | ATMSIRT1MAOAMAOBMEN1 | |
| SCHEMBL27014130 | 0.86 | SMN1; SMN2 (0.39) | ATMSIRT1MAOAMAOBMEN1 | |
| SCHEMBL27014131 | 0.86 | SMN1; SMN2 (0.39) | ATMSIRT1MAOAMAOBMEN1 | |
| SCHEMBL29587368 | 0.82 | HDAC4 (0.49) | — | |
| SCHEMBL24496708 | 0.82 | HDAC4 (0.49) | — | |
| SCHEMBL29586933 | 0.81 | KMT2A (0.41) | ATMMEN1KMT2A | |
| SCHEMBL24496707 | 0.81 | KMT2A (0.41) | ATMMEN1KMT2A | |
| SCHEMBL29586848 | 0.81 | KMT2A (0.41) | ATMMEN1KMT2A | |
| SCHEMBL6327261 | 0.81 | KMT2A (0.41) | ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206848-A | Substituted cycloalkyl compounds as modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-03-18 | — | — | CN | disclosed |