Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.65 |
| ▸ | DRD3 | P35462 | 3/20 | 0.65 |
| ▸ | HTR2C | P28335 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.65 |
| ▸ | HRH1 | P35367 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229524 | 1.00 | SIGMAR1 (0.72) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL25630644 | 0.88 | CYP3A4 (0.65) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL25630447 | 0.87 | SIGMAR1 (0.64) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL25630645 | 0.85 | SIGMAR1 (0.52) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL28728482 | 0.85 | HTR2A (0.68) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| Stearic Acid SCHEMBL8610949 | 0.84 | HTR2A (0.68) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL12648288 | 0.84 | SIGMAR1 (1.00) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL28403791 | 0.83 | SIGMAR1 (0.76) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL8091253 | 0.82 | SIGMAR1 (0.97) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL6422930 | 0.82 | SIGMAR1 (0.72) | SIGMAR1CYP3A4CYP2D6CYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276264-B | Fenfluramine hapten, artificial antigen, antibody, preparation method and application thereof | 华南农业大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-114276264-A | Fenfluramine hapten, artificial antigen, antibody, preparation method and application thereof | 华南农业大学 | 2022-04-05 | — | — | CN | disclosed |