Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549763 | 0.76 | MGAM (0.44) | MGAMALDH1A1ALOX15HPGDHSD17B10 | |
| SCHEMBL22453989 | 0.76 | MGAM (0.44) | MGAMALDH1A1ALOX15HPGDHSD17B10 | |
| SCHEMBL29499630 | 0.76 | MEN1 (0.41) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL29911576 | 0.73 | CYP1A2 (0.39) | ALDH1A1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL29499653 | 0.72 | DGKZ (0.36) | — | |
| SCHEMBL30547717 | 0.71 | MGAM (0.47) | MGAMALDH1A1ALOX15HPGDHSD17B10 | |
| SCHEMBL30912106 | 0.71 | MAPT (0.42) | ALDH1A1HSD17B10KDM4EL3MBTL1MEN1 | |
| SCHEMBL29499648 | 0.68 | RPS6KA5 (0.42) | ALDH1A1HPGDHSD17B10KDM4ENPC1 | |
| SCHEMBL29499620 | 0.68 | MTOR (0.37) | ALDH1A1ALOX15HPGDHSD17B10TSHR | |
| SCHEMBL2175934 | 0.67 | MGAM (0.64) | MGAMALDH1A1ALOX15HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302884-B | Substituted pyridopyrimidinone compounds useful as T cell activators | 百时美施贵宝公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114302884-A | Substituted pyridopyrimidinone based compounds useful as T cell activators | 百时美施贵宝公司 | 2022-04-08 | — | — | CN | disclosed |