Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.51 |
| ▸ | CTSD | P07339 | 2/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.49 |
| ▸ | FNTA | P49354 | 4/20 | 0.48 |
| ▸ | FNTB | P49356 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31741300 | 0.93 | FNTA (0.50) | ENPEPFNTAFNTB | |
| SCHEMBL30331865 | 0.92 | ENPEP (0.45) | BACE1BACE2ENPEPFNTAFNTB | |
| SCHEMBL29970445 | 0.90 | GNPAT (0.47) | BACE1BACE2ENPEPFNTAFNTB | |
| SCHEMBL31341151 | 0.88 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL5194261 | 0.88 | ENPEP (0.55) | BACE1BACE2CTSDENPEP | |
| SCHEMBL31089740 | 0.88 | ENPEP (0.55) | BACE1BACE2CTSDENPEP | |
| SCHEMBL29678007 | 0.88 | GNPAT (0.48) | ENPEPFNTAFNTB | |
| SCHEMBL31341136 | 0.88 | BACE1 (0.53) | BACE1BACE2CTSD | |
| SCHEMBL30578948 | 0.87 | BACE1 (0.43) | BACE1BACE2CTSDFNTAFNTB | |
| SCHEMBL29874270 | 0.87 | ENPEP (0.58) | BACE1BACE2CTSDENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201510-A1 | USE OF A FKBP51 INHIBITOR IN THE MANUFACTURE OF A MEDICAMENT FOR TREATING OR PREVENTING DISEASES CAUSED BY MITOCHONDRIAL ABNORMALITIES | TIANJIN UNIVERSITY (CN) | 2025-10-02 | — | — | WO | disclosed |
| US-20250064933-A1 | CHIMERIC ANTIGEN RECEPTORS COMPRISING A PDZ BINDING MOTIF | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| CN-115974828-B | Compounds as protein phosphatase 5 agonists, methods of preparation and uses thereof | 中国药科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-119302958-A | Application of pharmaceutical preparation containing BAY 73-6691 or derivatives thereof in preparing medicine for treating brain injury diseases | 郑州大学第一附属医院 | 2025-01-14 | — | — | CN | disclosed |
| WO-2024243078-A1 | HSP90 INHIBITORS FOR THE TREATMENT OF CANCER | LEAPFROG BIO, INC. (US) | 2024-11-28 | — | — | WO | disclosed |
| US-20230395193-A1 | SYSTEMS FOR AND METHODS OF TREATMENT SELECTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-12-07 | — | — | US | disclosed |
| CN-115974828-A | Compound as protein phosphatase 5 agonist and preparation method and application thereof | 中国药科大学 | 2023-04-18 | — | — | CN | disclosed |
| WO-2022081920-A1 | SYSTEMS FOR AND METHODS OF TREATMENT SELECTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |