Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25389374 | 1.00 | MAPK1 (0.42) | MAPK1MEN1KMT2AMAP2K7CYP1A2 | |
| SCHEMBL28629361 | 0.91 | MEN1 (0.37) | MAPK1MEN1KMT2AMAP2K7CYP1A2 | |
| SCHEMBL29501387 | 0.84 | MEN1 (0.37) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28999535 | 0.84 | MEN1 (0.37) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29501437 | 0.82 | CYP1A2 (0.49) | MAPK1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL28883687 | 0.82 | CYP1A2 (0.49) | MAPK1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL28999380 | 0.79 | HRH4 (0.46) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28999356 | 0.79 | MEN1 (0.40) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15229185 | 0.76 | MEN1 (0.71) | MAPK1MEN1KMT2AMAP2K7CYP1A2 | |
| SCHEMBL15830049 | 0.76 | MAPK1 (0.50) | MAPK1MEN1KMT2AMAP2K7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113626-A | Compound with anti-tumor activity and application thereof | 上海翊石医药科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2022048631-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-03-10 | — | — | WO | disclosed |