Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657988 | 1.00 | SLC18A3 (0.53) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL5271851 | 0.98 | SLC18A3 (0.51) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| Bromide SCHEMBL6423364 | 0.98 | SLC18A3 (0.51) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL29877056 | 0.98 | SLC18A3 (0.51) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL16835555 | 0.98 | SLC18A3 (0.51) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL22432705 | 0.94 | SLC18A3 (0.51) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL29501431 | 0.94 | SLC18A3 (0.51) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL30823789 | 0.92 | SLC18A3 (0.50) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL22418694 | 0.92 | SLC18A3 (0.50) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL29501433 | 0.90 | SLC18A3 (0.50) | SLC18A3HTR2CHTR2BHTR2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330009-B | Azacyclic compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2022237858-A1 | COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-11-17 | — | — | WO | disclosed |
| WO-2022048631-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-03-10 | — | — | WO | disclosed |