Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23684061 | 1.00 | PRMT5 (0.56) | PRMT5MAPTPTPN1EPHX2KDM4E | |
| SCHEMBL29501397 | 1.00 | PRMT5 (0.56) | PRMT5MAPTPTPN1EPHX2KDM4E | |
| SCHEMBL23684408 | 0.92 | PRMT5 (0.49) | PRMT5MAPTPTPN1EPHX2KDM4E | |
| SCHEMBL644335 | 0.87 | PRMT5 (0.60) | PRMT5MAPTEPHX2KDM4ELMNA | |
| SCHEMBL25386374 | 0.87 | PRMT5 (0.54) | PRMT5MAPTPTPN1EPHX2KDM4E | |
| SCHEMBL15829967 | 0.83 | EPHX2 (0.54) | PRMT5MAPTPTPN1EPHX2KDM4E | |
| SCHEMBL17560246 | 0.83 | MAPT (0.63) | PRMT5MAPTEPHX2 | |
| SCHEMBL17572113 | 0.83 | ALDH1A1 (0.61) | MAPTPTPN1EPHX2KDM4ELMNA | |
| SCHEMBL23684649 | 0.83 | PRMT5 (0.53) | PRMT5MAPTPTPN1EPHX2KDM4E | |
| SCHEMBL29817831 | 0.81 | MEN1 (0.52) | MAPTKDM4ELMNAGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113626-A | Compound with anti-tumor activity and application thereof | 上海翊石医药科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2022048631-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-03-10 | — | — | WO | disclosed |