Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26248522 | 0.97 | HRH4 (0.51) | HRH4DPP4SMOADRA1ASCN9A | |
| SCHEMBL26254464 | 0.91 | HRH4 (0.49) | HRH4DPP4SMOADRA1ASCN9A | |
| SCHEMBL26254803 | 0.90 | HRH4 (0.50) | HRH4DPP4SMOADRA1ASCN9A | |
| SCHEMBL29501378 | 0.90 | HRH4 (0.50) | HRH4DPP4SMOADRA1ASCN9A | |
| SCHEMBL26248111 | 0.86 | PRMT5 (0.54) | HRH4ADRA1ASCN9APRMT5WDR77 | |
| SCHEMBL25387542 | 0.85 | PRMT5 (0.50) | HRH4DPP4SCN9APRMT5WDR77 | |
| SCHEMBL26254679 | 0.85 | PRMT5 (0.50) | HRH4DPP4SCN9APRMT5WDR77 | |
| SCHEMBL25387544 | 0.85 | PRMT5 (0.50) | HRH4DPP4SCN9APRMT5WDR77 | |
| SCHEMBL26248126 | 0.84 | SCN9A (0.53) | HRH4SMOADRA1ASCN9ACHRM4 | |
| SCHEMBL29501410 | 0.82 | SCN9A (0.50) | HRH4SMOADRA1ASCN9ACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048631-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-03-10 | — | — | WO | disclosed |