SCHEMBL29501735

SCHEMBL29501735

COC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CCl)COC12

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 11/20 0.40
ELANE P08246 9/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501744 0.78 CMA1 (0.55) CMA1ELANE
SCHEMBL29501738 0.78 CMA1 (0.49) CMA1ELANE
SCHEMBL11140147 0.76 CMA1 (0.38) CMA1
SCHEMBL10904639 0.72 PTGS1 (0.52)
SCHEMBL2150208 0.71 HSD17B10 (0.47)
SCHEMBL5498934 0.71 HSD17B10 (0.47)
SCHEMBL2150205 0.71 HSD17B10 (0.47)
SCHEMBL9567700 0.71 HSD17B10 (0.47)
SCHEMBL12047940 0.71 HSD17B10 (0.47)
SCHEMBL5498935 0.71 HSD17B10 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315865-A Flomoxef process impurity and preparation method thereof 北京济美堂医药研究有限公司 2022-04-12 CN claimed
CN-114315865-A Flomoxef process impurity and preparation method thereof 北京济美堂医药研究有限公司 2022-04-12 CN disclosed