Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 10/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142262 | 0.90 | CYP2D6 (0.40) | CMA1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL11144720 | 0.82 | MAPK1 (0.47) | CMA1ALDH1A1HSD17B10MAPTBLM | |
| SCHEMBL10980179 | 0.81 | ALDH1A1 (0.36) | CMA1ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL11136153 | 0.80 | CTDSP1 (0.40) | ALDH1A1 | |
| SCHEMBL11144310 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HPGDHSD17B10MAPTBLM | |
| SCHEMBL11056700 | 0.78 | HSD17B10 (0.53) | ESR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10858773 | 0.78 | HSD17B10 (0.53) | ESR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10584406 | 0.78 | HSD17B10 (0.53) | ESR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10833692 | 0.78 | HSD17B10 (0.53) | ESR1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11056697 | 0.78 | HSD17B10 (0.53) | ESR1ALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399135-A | ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1983-08-16 | — | — | US | disclosed |
| US-4370478-A | Oxacephalosporins | RHONE-POULENC INDUSTRIES (FR) | 1983-01-25 | — | — | US | disclosed |
| US-4369315-A | ANTIBIOTIC | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | disclosed |
| US-4369314-A | Oxacephalosporins | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | disclosed |