Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28162814 | 1.00 | LMNA (0.52) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL197618 | 1.00 | LMNA (0.52) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL29398319 | 1.00 | LMNA (0.52) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL28162815 | 1.00 | LMNA (0.52) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL29465008 | 1.00 | LMNA (0.52) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL24733 | 1.00 | LMNA (0.52) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL24732 | 1.00 | LMNA (0.52) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL28848826 | 0.98 | LMNA (0.50) | LMNAMAPK1FABP4FABP5CASP1 | |
| Hydrochloric Acid SCHEMBL1374028 | 0.98 | LMNA (0.50) | LMNAMAPK1FABP4FABP5CASP1 | |
| SCHEMBL28180751 | 0.98 | LMNA (0.50) | LMNAMAPK1FABP4FABP5CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178202-B | (N- (R) -alpha-phenethyl) nitrilotriacetamide and preparation method and application thereof | 广西大学 | 2025-05-06 | — | — | CN | claimed |
| US-20250084395-A1 | ENGINEERED NITRILASES FOR BIOCATALYSIS | KCAT ENZYMATIC PRIVATE LIMITED (IN) | 2025-03-13 | — | — | US | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-113754726-B | Recombinant enzyme containing polypeptide tag and application thereof in synthesis of medicinal chemicals | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| CN-113801239-B | Polypeptide tag, highly soluble recombinant nitrilase and application thereof in synthesis of medicinal chemicals | 浙江工业大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116655652-A | New synthesis method of clopidogrel | 宿迁盛基医药科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116178202-A | (N- (R) -alpha-phenethyl) nitrilotriacetamide and preparation method and application thereof | 广西大学 | 2023-05-30 | — | — | CN | claimed |
| WO-2022095221-A1 | POLYPEPTIDE TAG, HIGHLY SOLUBLE RECOMBINANT NITRILASE, AND APPLICATION THEREOF IN PHARMACEUTICAL CHEMICAL SYNTHESIS | 浙江工业大学 | 2022-05-12 | — | — | WO | claimed |
| CN-116178202-B | (N- (R) -alpha-phenethyl) nitrilotriacetamide and preparation method and application thereof | 广西大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-116178202-B | (N- (R) -alpha-phenethyl) nitrilotriacetamide and preparation method and application thereof | 广西大学 | 2025-05-06 | — | — | CN | disclosed |
| US-20250084395-A1 | ENGINEERED NITRILASES FOR BIOCATALYSIS | KCAT ENZYMATIC PRIVATE LIMITED (IN) | 2025-03-13 | — | — | US | disclosed |
| CN-118931887-A | Nitrilase cross-linked enzyme aggregate, and preparation method and application thereof | 浙江工业大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-113355367-B | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2024-03-26 | — | — | CN | disclosed |
| WO-2022095221-A1 | POLYPEPTIDE TAG, HIGHLY SOLUBLE RECOMBINANT NITRILASE, AND APPLICATION THEREOF IN PHARMACEUTICAL CHEMICAL SYNTHESIS | 浙江工业大学 | 2022-05-12 | — | — | WO | disclosed |
| US-20220135960-A1 | POLYPEPTIDE TAG, HIGHLY SOLUBLE RECOMBINANT NITRILASE AND APPLICATION THEREOF IN SYNTHESIS OF PHARMACEUTICAL CHEMICALS | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2022-05-05 | — | — | US | disclosed |
| CN-110172021-B | Separation and extraction method of (R) -o-chloromandelic acid | 武汉武药制药有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-110183355-B | Refining method of high-purity o-chloro mandelonitrile | 武汉武药制药有限公司 | 2022-04-22 | — | — | CN | disclosed |
| US-20220113247-A1 | QUANTITATIVE AUXILIARY-FREE CHIRALITY SENSING WITH A METAL PROBE | GEORGETOWN UNIVERSITY | 2022-04-14 | — | — | US | disclosed |
| CN-109867685-B | Preparation method of clopidogrel hydrogen sulfate II type | 武汉武药制药有限公司 | 2022-04-08 | — | — | CN | disclosed |