Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807342 | 0.96 | RET (0.47) | RETKCNK3KCNK9AR | |
| SCHEMBL2943421 | 0.94 | AR (0.43) | ARS1PR1 | |
| SCHEMBL2950177 | 0.92 | PPARA (0.50) | ARS1PR1 | |
| SCHEMBL2942158 | 0.90 | AR (0.43) | ARS1PR1 | |
| SCHEMBL23607575 | 0.87 | KCNK3 (0.48) | KCNK3KCNK9S1PR1 | |
| SCHEMBL29711728 | 0.86 | TRPV1 (0.48) | RETKCNK3KCNK9S1PR1 | |
| SCHEMBL29371081 | 0.86 | TRPV1 (0.48) | RETKCNK3KCNK9S1PR1 | |
| SCHEMBL998270 | 0.86 | TRPV1 (0.48) | RETKCNK3KCNK9S1PR1 | |
| SCHEMBL18804890 | 0.86 | AR (0.46) | ARS1PR1 | |
| SCHEMBL2943417 | 0.83 | AR (0.48) | KCNK3KCNK9AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167107-A1 | Modulators (inhibitors/ activators) of histone acetyltransferases | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2006-07-27 | — | — | US | claimed |
| US-7750047-B2 | Modulators (inhibitors/activators) of histone acetyltransferases | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2010-07-06 | — | — | US | disclosed |
| US-20090076155-A1 | MODULATORS (INHIBITORS/ACTIVATORS) OF HISTONE ACETYLTRANSFERASES | KUNDU TAPAS KUMAR | 2009-03-19 | — | — | US | disclosed |
| US-7332629-B2 | Modulators (inhibitors/activators) of histone acetyltransferases | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2008-02-19 | — | — | US | disclosed |
| US-20060167107-A1 | Modulators (inhibitors/ activators) of histone acetyltransferases | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2006-07-27 | — | — | US | disclosed |
| EP-1590318-A2 | MODULATORS (INHIBITORS/ACTIVATORS) OF HISTONE ACETYLTRANSFERASES | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004053140-A2 | MODULATORS (INHIBITORS/ACTIVATORS) OF HISTONE ACETYLTRANSFERASES | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167107-A1 | Modulators (inhibitors/ activators) of histone acetyltransferases | EP300, HDAC1, KAT2A | RET 4625/4885KCNK3 3907/4885KCNK9 2957/4885 |
| US-20090076155-A1 | MODULATORS (INHIBITORS/ACTIVATORS) OF HISTONE ACETYLTRANSFERASES | KAT2A, HDAC5, HAT1 | RET 2777/4885KCNK3 3703/4885KCNK9 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.