Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.52 |
| ▸ | NPY1R | P25929 | 9/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.52 |
| ▸ | NPY2R | P49146 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.48 |
| ▸ | TFPI | P10646 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405659 | 0.98 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL30512013 | 0.94 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL30211355 | 0.94 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| Laminin SCHEMBL2182807 | 0.92 | OPRD1 (0.55) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| Laminin SCHEMBL2182800 | 0.92 | OPRD1 (0.55) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL30211356 | 0.90 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL29472195 | 0.90 | F2 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL29502171 | 0.88 | QRFPR (0.57) | NPY4RNPY1RNPY2ROPRD1OPRK1 | |
| SCHEMBL29679859 | 0.87 | TFPI (0.56) | NPY4RNPY1RNPY5RTFPI | |
| SCHEMBL31261768 | 0.87 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RQRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167405-A1 | METHODS AND COMPOSITIONS OF PRO-ORGAN FORMATION ON PARTICLE SUBSTRATES AND USES THEREOF | HEROPHILUS, INC. | 2023-06-01 | — | — | US | disclosed |
| EP-4087914-A1 | METHODS AND COMPOSITIONS OF PRO-ORGAN FORMATION ON PARTICLE SUBSTRATES AND USES THEREOF | Herophilus, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |
| CN-109134603-B | 1, 1-dihydroxymethyl-tetrahydro-beta-carboline-3-formyl-GYIGSR, and synthesis, activity and application thereof | 首都医科大学 | 2022-04-22 | — | — | CN | disclosed |