Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | CDK4 | P11802 | 2/20 | 0.50 |
| ▸ | CCND1 | P24385 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18703278 | 1.00 | MAOB (0.54) | MAOBACHECDK4CCND1CCNB2 | |
| SCHEMBL5087354 | 0.87 | MAOB (0.53) | MAOBACHECDK4CCND1CCNB2 | |
| SCHEMBL13577008 | 0.83 | ACHE (0.49) | MAOBACHECDK4CCND1CCNB2 | |
| SCHEMBL20526908 | 0.81 | MAOB (0.56) | MAOBALOX5 | |
| SCHEMBL18702902 | 0.79 | MAOB (0.49) | MAOBACHECDK4CCND1CCNB2 | |
| SCHEMBL21340421 | 0.78 | MAOB (0.61) | MAOBACHECDK4CCND1CCNB2 | |
| SCHEMBL5090936 | 0.78 | MAOB (0.48) | MAOBACHESLC26A4FFAR1KMT2A | |
| SCHEMBL4638503 | 0.78 | MAOB (0.60) | MAOBACHECDK4CCND1CCNB2 | |
| SCHEMBL31172168 | 0.78 | MAOB (0.60) | MAOBACHECDK4CCND1CCNB2 | |
| SCHEMBL13577234 | 0.77 | CACNA1C (0.48) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430994-B | Compounds, compositions and methods for modulating CFTR | 蛋白质平衡治疗股份有限公司 | 2022-04-12 | — | — | CN | disclosed |