Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249663 | 0.95 | CES2 (0.51) | CES2CES1ALDH1A1HPGDHTT | |
| SCHEMBL13808811 | 0.95 | CES2 (0.51) | CES2CES1ALDH1A1HPGDHTT | |
| SCHEMBL27657632 | 0.86 | CES2 (0.66) | CES2CES1MEN1MAPTKMT2A | |
| SCHEMBL28180756 | 0.86 | CES2 (0.66) | CES2CES1MEN1MAPTKMT2A | |
| SCHEMBL17936731 | 0.85 | CES2 (0.51) | CES2CES1ALDH1A1HPGD | |
| SCHEMBL22550043 | 0.85 | HTT (0.47) | CES2CES1ALDH1A1HPGDHTT | |
| SCHEMBL14389493 | 0.83 | CES2 (0.49) | CES2CES1ALDH1A1HPGD | |
| SCHEMBL12021972 | 0.81 | CES2 (0.48) | CES2CES1ALDH1A1HPGDMAPT | |
| SCHEMBL92006 | 0.81 | CES2 (0.48) | CES2CES1ALDH1A1HPGDMAPT | |
| SCHEMBL22729193 | 0.81 | CES2 (0.48) | CES2CES1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119126490-A | Preparation method and application of low-residual-stress high-refractive-index negative OC photoresist and photo-curing pattern | 西安思摩威新材料有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114326299-A | Photosensitive resin composition, optical filter and application | 常州强力电子新材料股份有限公司 | 2022-04-12 | — | — | CN | disclosed |