SCHEMBL29503159

SCHEMBL29503159

Cc1cncc(C(N)=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.67
ATM Q13315 1/20 0.60
PARP1 P09874 1/20 0.50
SMYD3 Q9H7B4 2/20 0.49
RAF1 P04049 1/20 0.49
PKMYT1 Q99640 1/20 0.49
MKNK1 Q9BUB5 5/20 0.47
MKNK2 Q9HBH9 5/20 0.47
SIRT2 Q8IXJ6 4/20 0.45
SIRT1 Q96EB6 4/20 0.45
SIRT3 Q9NTG7 4/20 0.45
F7 P08709 1/20 0.45
F3 P13726 1/20 0.45
SARM1 Q6SZW1 1/20 0.45
SIRT6 Q8N6T7 1/20 0.45
SIRT5 Q9NXA8 1/20 0.45
SIRT4 Q9Y6E7 1/20 0.45
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
MAP4K4 O95819 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL832732 1.00 HCAR2 (0.67) HCAR2ATMPARP1SMYD3RAF1
Hydrochloric Acid SCHEMBL27809845 0.98 HCAR2 (0.64) HCAR2ATMPARP1SMYD3RAF1
SCHEMBL2841794 0.84 SIRT2 (0.54) HCAR2RAF1PKMYT1MKNK1MKNK2
SCHEMBL29477599 0.83 HCAR2 (0.62) HCAR2ATMPARP1SMYD3RAF1
SCHEMBL30892620 0.82 HCAR2 (0.50) HCAR2ATMPARP1SMYD3RAF1
Hydrazine SCHEMBL28220034 0.81 HCAR2 (0.92) HCAR2ATMSMYD3RAF1MKNK1
SCHEMBL10274533 0.80 HCAR2 (0.58) HCAR2ATMSMYD3RAF1PKMYT1
SCHEMBL12164220 0.80 HCAR2 (0.58) HCAR2ATMPARP1SMYD3RAF1
SCHEMBL3102318 0.80 HCAR2 (0.69) HCAR2ATMSMYD3MKNK1MKNK2
SCHEMBL29586507 0.80 HCAR2 (1.00) HCAR2ATMSMYD3RAF1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709405-A2 FLUORESCEIN-LABELED NERVE TARGETING PEPTIDE FORMULATIONS AND RELATED METHODS Alume Biosciences, Inc. (US) 2026-03-18 EP disclosed
US-20250230155-A1 7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS VANDERBILT UNIVERSITY 2025-07-17 US disclosed
EP-4554683-A2 METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS Lantern Pharma Inc. (US) 2025-05-21 EP disclosed
EP-4484952-A2 OPTIMIZED PEPTIDES FOR TARGETING HUMAN NERVES AND THEIR USE IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY The Regents of the University of California (US) 2025-01-01 EP disclosed
WO-2024233683-A2 FLUORESCEIN-LABELED NERVE TARGETING PEPTIDE FORMULATIONS AND RELATED METHODS ALUME BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed
EP-3661539-B1 OPTIMIZED PEPTIDES FOR TARGETING HUMAN NERVES AND THEIR USE IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY UNIV CALIFORNIA (US) 2024-10-09 EP disclosed
EP-4376822-A1 TREATING CANCERS WITH COMBINATIONS OF PARP INHIBITOR AND ACYLFULVENES Lantern Pharma Inc. (US) 2024-06-05 EP disclosed
WO-2024016014-A2 METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS LANTERN PHARMA INC. (US) 2024-01-18 WO disclosed
US-20230102554-A1 HETEROCYCLIC KINASE INHIBITORS AND PRODUCTS AND USES THEREOF GB002, INC. 2023-03-30 US disclosed
WO-2023010119-A1 TREATING CANCERS WITH COMBINATIONS OF PARP INHIBITOR AND ACYLFULVENES LANTERN PHARMA INC. (US) 2023-02-02 WO disclosed
EP-4041311-A1 METHODS AND SYSTEMS USING PEPTIDES FOR TARGETING AND MAPPING HUMAN NERVES IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY Alume Biosciences, Inc. (US) 2022-08-17 EP disclosed
WO-2022120177-A1 NERVE TARGETING PEPTIDES AND METHODS OF USE ALUME BIOSCIENCES, INC. (US) 2022-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230102554-A1 HETEROCYCLIC KINASE INHIBITORS AND PRODUCTS AND USES THEREOF PDGFRB, PDGFRA, FGFR1 HCAR2 1417/4885ATM 651/4885PARP1 1786/4885
US-20250230155-A1 7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS CHRM5, CHRM4, CHRM1 HCAR2 419/4885ATM 2922/4885PARP1 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.