Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.45 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354553 | 1.00 | LCK (0.48) | LCKCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL3352794 | 0.85 | CTNNB1 (0.57) | LCKCHRNA7HTR3APARP1DYRK1A | |
| SCHEMBL29503181 | 0.85 | CTNNB1 (0.57) | LCKCHRNA7HTR3APARP1DYRK1A | |
| SCHEMBL1891764 | 0.82 | MRGPRX4 (0.55) | CHRNA7HTR3AHTR3EHTR3BCHRNB4 | |
| SCHEMBL30445266 | 0.82 | MRGPRX4 (0.55) | CHRNA7HTR3AHTR3EHTR3BCHRNB4 | |
| SCHEMBL5591790 | 0.81 | PLAU (0.50) | CHRNA7HTR3AHTR3EHTR3BCHRNB4 | |
| SCHEMBL19756724 | 0.81 | CHRNA7 (0.45) | CHRNA7HTR3AHTR3EHTR3BCHRNB4 | |
| SCHEMBL3797885 | 0.81 | CA2 (0.49) | CHRNA7HTR3AHTR3EHTR3BCHRNB4 | |
| Hydrochloric Acid SCHEMBL31483491 | 0.81 | MRGPRX4 (0.54) | CHRNA7HTR3AHTR3EHTR3BCHRNB4 | |
| Hydrochloric Acid SCHEMBL9431571 | 0.79 | PLAU (0.48) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073502-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-04 | — | — | WO | disclosed |