Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19743665 | 1.00 | EIF2AK3 (0.59) | EIF2AK3 | |
| SCHEMBL19743297 | 0.83 | ABL1 (0.49) | — | |
| SCHEMBL29503473 | 0.83 | ABL1 (0.49) | — | |
| SCHEMBL22418461 | 0.80 | FLT3 (0.62) | — | |
| SCHEMBL20351737 | 0.78 | ABL1 (0.66) | EIF2AK3 | |
| SCHEMBL19743355 | 0.77 | EIF2AK3 (0.77) | EIF2AK3 | |
| SCHEMBL19743662 | 0.77 | EIF2AK3 (0.59) | EIF2AK3 | |
| SCHEMBL19743322 | 0.76 | EIF2AK3 (0.62) | EIF2AK3 | |
| SCHEMBL30544150 | 0.76 | EIF2AK3 (0.62) | EIF2AK3 | |
| Hydrochloric Acid SCHEMBL19743287 | 0.75 | EIF2AK3 (0.61) | EIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11491158-B2 | N-(substituted-phenyl)-sulfonamide derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2022-11-08 | — | — | US | disclosed |
| CN-109311894-B | N- (substituted-phenyl) -sulfonamide derivatives as kinase inhibitors | 内尔维阿诺医学科学有限公司 | 2022-03-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11491158-B2 | N-(substituted-phenyl)-sulfonamide derivatives as kinase inhibitors | ATF4, MAP3K1, MAP3K6 | EIF2AK3 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.