Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22716255 | 1.00 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL29503767 | 0.93 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL22716444 | 0.93 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL22730143 | 0.87 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL32663023 | 0.87 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL22727708 | 0.86 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL29503749 | 0.86 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL29503848 | 0.81 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL22716380 | 0.81 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE10A | |
| SCHEMBL32663017 | 0.81 | PDE2A (0.42) | PDE4APDE4BPDE4CPDE4DPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12458021-B2 | Microbiocidal derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2025-11-04 | — | — | US | disclosed |
| CN-113874353-B | Microbiocidal derivatives | 先正达农作物保护股份公司 | 2024-06-14 | — | — | CN | disclosed |
| US-20220272976-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-09-01 | — | — | US | disclosed |
| EP-3976586-A1 | MICROBIOCIDAL DERIVATIVES | Syngenta Crop Protection AG (CH) | 2022-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220272976-A1 | MICROBIOCIDAL DERIVATIVES | MPO, MSR1, PRF1 | PDE4A 990/4885PDE4B 867/4885PDE4C 1076/4885 |
| US-12458021-B2 | Microbiocidal derivatives | MPO, MSR1, PRF1 | PDE4A 990/4885PDE4B 867/4885PDE4C 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.