SCHEMBL29504606

SCHEMBL29504606

C=CCOC(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)[C@@H](C)O

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.49
EPHX2 P34913 1/20 0.46
KMT2A Q03164 2/20 0.46
PIN1 Q13526 1/20 0.44
MDM4 O15151 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29609769 0.92 CASP3 (0.55) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL29787101 0.87 CASP3 (0.51) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL5057040 0.87 CASP3 (0.55) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL8234025 0.87 CASP3 (0.49) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL8256929 0.87 CASP3 (0.55) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL8258239 0.87 CASP3 (0.55) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL30317387 0.87 CASP3 (0.49) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL7317762 0.86 CASP3 (0.52) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL7390390 0.86 CASP3 (0.52) CASP3EPHX2KMT2APIN1MDM4
SCHEMBL17256589 0.86 CASP3 (0.52) CASP3EPHX2KMT2APIN1MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315963-B LSH series cyclic pentapeptide ester and synthetic method and application thereof 河北科技大学 2023-11-17 CN disclosed
CN-114315963-A LSH series cyclic pentapeptide ester and synthetic method and application thereof 河北科技大学 2022-04-12 CN disclosed