Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | PDE8B | O95263 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122955 | 0.88 | PARP1 (0.41) | KDM1APRMT5OPRD1HCRTR2MEN1 | |
| SCHEMBL31122919 | 0.88 | USP30 (0.40) | KDM1APRMT5PDE8BOPRD1HCRTR2 | |
| SCHEMBL31122974 | 0.88 | USP30 (0.40) | KDM1APRMT5PDE8BOPRD1HCRTR2 | |
| SCHEMBL31048209 | 0.87 | GPR119 (0.38) | KDM1AOPRD1ALOX5APFEN1HCRTR2 | |
| SCHEMBL31048364 | 0.86 | PARP1 (0.38) | KDM1AHCRTR2MEN1KMT2ATSHR | |
| SCHEMBL31048363 | 0.86 | PARP1 (0.37) | KDM1AOPRD1ALOX5APFEN1HCRTR2 | |
| SCHEMBL31048405 | 0.86 | PARP1 (0.39) | KDM1AOPRD1HCRTR2MEN1KMT2A | |
| SCHEMBL31122981 | 0.85 | KDM1A (0.36) | KDM1AOPRD1ALOX5APFEN1HCRTR2 | |
| SCHEMBL31122948 | 0.85 | GPR119 (0.38) | KDM1AOPRD1HCRTR2MEN1KMT2A | |
| SCHEMBL25568115 | 0.85 | GPR119 (0.38) | KDM1AOPRD1HCRTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805280-B | Heteroaryl compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-110785420-B | Oxazepin derivatives as inhibitors of PI 3-kinase activity | 葛兰素史克知识产权开发有限公司 | 2022-04-26 | — | — | CN | disclosed |