Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B3GAT3 | O94766 | 1/20 | 0.79 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984931 | 1.00 | B3GAT3 (0.79) | B3GAT3CDK4CCND1SOS1LMNA | |
| SCHEMBL28984921 | 0.91 | B3GAT3 (0.79) | B3GAT3CDK4CCND1NR4A2 | |
| SCHEMBL29504687 | 0.91 | B3GAT3 (0.79) | B3GAT3CDK4CCND1NR4A2 | |
| SCHEMBL29504741 | 0.91 | B3GAT3 (0.79) | B3GAT3CDK4CCND1 | |
| SCHEMBL28984923 | 0.91 | B3GAT3 (0.78) | B3GAT3CDK4CCND1 | |
| SCHEMBL28984922 | 0.90 | B3GAT3 (0.85) | B3GAT3CDK4CCND1LMNARAB9A | |
| SCHEMBL29504777 | 0.90 | B3GAT3 (0.76) | B3GAT3CDK4CCND1RAB9ATP53 | |
| SCHEMBL29504658 | 0.89 | B3GAT3 (0.81) | B3GAT3LMNARAB9ANR4A2TP53 | |
| SCHEMBL28984920 | 0.89 | B3GAT3 (0.75) | B3GAT3CDK4CCND1NR4A2TP53 | |
| SCHEMBL30267518 | 0.88 | B3GAT3 (1.00) | B3GAT3CDK4CCND1RAB9ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974849-A | Indoxyl acetamide derivative, pharmaceutical composition containing indoxyl acetamide derivative and application of indoxyl acetamide derivative | 中国药科大学 | 2023-04-18 | — | — | CN | claimed |
| CN-114456150-A | NR2B receptor antagonist or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2022-05-10 | — | — | CN | claimed |
| CN-115974849-B | Indolyloxy acetamide derivative, pharmaceutical composition containing same and application of pharmaceutical composition | 中国药科大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-115974849-A | Indoxyl acetamide derivative, pharmaceutical composition containing indoxyl acetamide derivative and application of indoxyl acetamide derivative | 中国药科大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-114456150-A | NR2B receptor antagonist or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2022-05-10 | — | — | CN | disclosed |