Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389229 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29506319 | 0.81 | GAA (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28389941 | 0.81 | GAA (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29506274 | 0.81 | GAA (0.69) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29506302 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28391228 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29506305 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28392626 | 0.78 | GAA (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29506279 | 0.78 | GAA (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28393245 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110964018-B | Indole derivative and application thereof | 华侨大学 | 2022-03-11 | — | — | CN | disclosed |