Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.59 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17228831 | 1.00 | MAP3K11 (0.59) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL30883881 | 1.00 | MAP3K11 (0.59) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL19991873 | 0.90 | MAP3K11 (0.56) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL18086412 | 0.88 | MAP3K11 (0.51) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL17465511 | 0.88 | MAP3K11 (0.51) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL19988527 | 0.87 | MAP3K11 (0.52) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL22011438 | 0.86 | MAP3K11 (0.53) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL22011385 | 0.86 | MAP3K11 (0.53) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL18688088 | 0.85 | MAP3K11 (0.49) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A | |
| SCHEMBL18688086 | 0.85 | MAP3K11 (0.49) | MAP3K11MAP3K9CDK5CDK5R1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978491-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | Merck Patent GmbH (DE) | 2022-04-06 | — | — | EP | disclosed |