SCHEMBL29506416

SCHEMBL29506416

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.48
▸ NPY1R P25929 9/20 0.48
▸ NPY5R Q15761 8/20 0.48
▸ NPY2R P49146 5/20 0.48
▸ PTGS1 P23219 1/20 0.44
▸ GSTK1 Q9Y2Q3 1/20 0.44
▸ OPRM1 P35372 2/20 0.41
▸ OPRD1 P41143 2/20 0.41
▸ OPRK1 P41145 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30272464 0.92 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30786580 0.91 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL29896074 0.91 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL30786583 0.89 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL29576011 0.89 OPRD1 (0.49) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL29420510 0.89 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL30946719 0.88 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31752209 0.87 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30661263 0.87 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2R
SCHEMBL3138301 0.87 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240316170-A1 POLYPEPTIDES FOR CANCER TREATMENT Oxford Vacmedix UK Limited (GB) 2024-09-26 — — US disclosed
EP-4236994-A1 POLYPEPTIDES FOR CANCER TREATMENT Oxford Vacmedix UK Ltd. (GB) 2023-09-06 — — EP disclosed
CN-116406284-A Polypeptides for cancer treatment 牛津疫苗医学公司 2023-07-07 — — CN disclosed
WO-2022090679-A1 CORONAVIRUS POLYPEPTIDE Oxford Vacmedix UK Limited (GB) 2022-05-05 — — WO disclosed
WO-2022090716-A1 POLYPEPTIDES FOR CANCER TREATMENT Oxford Vacmedix UK Limited (GB) 2022-05-05 — — WO disclosed
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