Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863885 | 0.82 | TLR7 (0.64) | TLR7TLR8NLRP3 | |
| SCHEMBL29371417 | 0.82 | TLR7 (0.64) | TLR7TLR8NLRP3 | |
| SCHEMBL29507673 | 0.80 | TLR7 (0.49) | TLR7TLR8NLRP3 | |
| SCHEMBL24428132 | 0.77 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL29035523 | 0.76 | TLR7 (0.41) | TLR7TLR8NLRP3 | |
| SCHEMBL30527213 | 0.76 | TLR7 (0.57) | TLR7TLR8NLRP3 | |
| SCHEMBL3862520 | 0.74 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL29374507 | 0.74 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL483282 | 0.71 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL30346099 | 0.71 | TLR7 (0.60) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381350-A1 | ANTIBODY FRAGMENT AGAINST FAP | PRECIRIX N.V. (BE) | 2023-11-30 | — | — | US | disclosed |
| WO-2023213801-A1 | PRE-TARGETING | PRECIRIX N.V. (BE) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023203135-A1 | IMPROVED RADIOLABELLED ANTIBODY | PRECIRIX N.V. (BE) | 2023-10-26 | — | — | WO | disclosed |
| EP-4211171-A2 | ANTIBODY FRAGMENT AGAINST FAP | Precirix N.V. (BE) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022053651-A2 | ANTIBODY FRAGMENT AGAINST FAP | PRECIRIX N.V. (BE) | 2022-03-17 | — | — | WO | disclosed |