Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373958 | 0.85 | TLR7 (0.69) | TLR7TLR8NUDT1 | |
| SCHEMBL3862215 | 0.85 | TLR7 (0.69) | TLR7TLR8NUDT1 | |
| SCHEMBL3868448 | 0.82 | TLR7 (0.58) | TLR7TLR8NUDT1DHFR | |
| SCHEMBL3861997 | 0.80 | TLR8 (0.57) | TLR7TLR8NUDT1DHFR | |
| SCHEMBL3867967 | 0.80 | TLR7 (0.53) | TLR7TLR8NUDT1 | |
| SCHEMBL29507665 | 0.80 | TLR7 (0.50) | TLR7TLR8NLRP3 | |
| SCHEMBL3866064 | 0.79 | TLR7 (0.68) | TLR7TLR8NUDT1DHFR | |
| SCHEMBL6105785 | 0.79 | TLR7 (0.50) | TLR7TLR8NUDT1 | |
| SCHEMBL13645600 | 0.79 | TLR7 (0.56) | TLR7TLR8NUDT1NLRP3 | |
| SCHEMBL3863711 | 0.79 | TLR7 (0.53) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381350-A1 | ANTIBODY FRAGMENT AGAINST FAP | PRECIRIX N.V. (BE) | 2023-11-30 | — | — | US | disclosed |
| WO-2023213801-A1 | PRE-TARGETING | PRECIRIX N.V. (BE) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023203135-A1 | IMPROVED RADIOLABELLED ANTIBODY | PRECIRIX N.V. (BE) | 2023-10-26 | — | — | WO | disclosed |
| EP-4211171-A2 | ANTIBODY FRAGMENT AGAINST FAP | Precirix N.V. (BE) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022053651-A2 | ANTIBODY FRAGMENT AGAINST FAP | PRECIRIX N.V. (BE) | 2022-03-17 | — | — | WO | disclosed |