Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899557 | 0.87 | CASP3 (0.47) | KDM4ECASP3KMT2AJMJD6MAPT | |
| SCHEMBL21138967 | 0.84 | BAZ2B (0.43) | KDM4EBAZ2BBAZ2AJMJD6MAPT | |
| SCHEMBL6219930 | 0.82 | CA12 (0.51) | KDM4EBAZ2BBAZ2ACYP1A2JMJD6 | |
| SCHEMBL1256450 | 0.80 | CREBBP (0.42) | SLC18A3PRMT5KDM4EKMT2AJMJD6 | |
| SCHEMBL12640247 | 0.80 | SLC18A3 (0.41) | SLC18A3PIK3C3PRMT5KDM4ETUBB4A | |
| SCHEMBL15069309 | 0.79 | ATM (0.41) | SLC18A3PIK3C3PRMT5KDM4ECYP1A2 | |
| SCHEMBL2304354 | 0.78 | BRD4 (0.49) | SLC18A3PRMT5KDM4EKMT2A | |
| SCHEMBL13702424 | 0.76 | HDAC8 (0.46) | SLC18A3PRMT5KMT2AMAPK8HDAC6 | |
| SCHEMBL13890783 | 0.76 | KDM4E (0.47) | SLC18A3PIK3C3PRMT5KDM4ETUBB4A | |
| SCHEMBL13876014 | 0.76 | SLC18A3 (0.39) | SLC18A3PIK3C3PRMT5KDM4ETUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728219-B1 | SUBSTITUTED PYRROLIDINE AMIDES I | GRUENENTHAL GMBH (DE) | 2022-04-13 | — | — | EP | disclosed |