Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749243 | 1.00 | TLR7 (0.39) | TLR7LMNAUSP5TLR8PDE4A | |
| SCHEMBL22749271 | 0.93 | USP5 (0.37) | TLR7LMNAUSP5TLR8PDE4A | |
| SCHEMBL29508406 | 0.91 | PDE4A (0.36) | TLR7LMNAUSP5TLR8PDE4A | |
| SCHEMBL29508398 | 0.88 | USP5 (0.39) | TLR7LMNAUSP5TLR8TSHR | |
| SCHEMBL29508409 | 0.83 | USP5 (0.40) | TLR7LMNAUSP5PDE4DTSHR | |
| SCHEMBL22749242 | 0.83 | USP5 (0.40) | TLR7LMNAUSP5PDE4DTSHR | |
| SCHEMBL21995110 | 0.83 | TLR7 (0.36) | TLR7USP5TLR8TSHR | |
| SCHEMBL21994853 | 0.83 | TLR7 (0.36) | TLR7USP5TLR8TSHR | |
| SCHEMBL22749284 | 0.80 | TLR7 (0.56) | TLR7LMNATLR8PDE4DKCNH2 | |
| SCHEMBL22749228 | 0.80 | TLR7 (0.56) | TLR7LMNATLR8PDE4DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |