Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749242 | 1.00 | USP5 (0.40) | USP5TSHRTLR7LMNAPOLB | |
| SCHEMBL29508398 | 0.88 | USP5 (0.39) | USP5TSHRTLR7LMNADUSP10 | |
| SCHEMBL22749271 | 0.85 | USP5 (0.37) | USP5TSHRTLR7LMNAPDE4D | |
| SCHEMBL22749243 | 0.83 | TLR7 (0.39) | USP5TSHRTLR7LMNAPDE4D | |
| SCHEMBL29508402 | 0.83 | TLR7 (0.39) | USP5TSHRTLR7LMNAPDE4D | |
| SCHEMBL22749324 | 0.83 | USP5 (0.44) | USP5TSHRTLR7LMNAPOLB | |
| SCHEMBL29508401 | 0.83 | USP5 (0.44) | USP5TSHRTLR7LMNAPOLB | |
| SCHEMBL21994853 | 0.82 | TLR7 (0.36) | USP5TSHRTLR7POLBNUDT1 | |
| SCHEMBL21995110 | 0.82 | TLR7 (0.36) | USP5TSHRTLR7POLBNUDT1 | |
| SCHEMBL10588967 | 0.82 | USP5 (0.42) | USP5TSHRTLR7LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |