Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 20/20 | 1.00 |
| ▸ | TNF | P01375 | 3/20 | 0.78 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22689434 | 1.00 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL22689433 | 1.00 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL22655208 | 1.00 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL22655128 | 1.00 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL22655032 | 1.00 | IL1B (1.00) | IL1BTNFNLRP3 | |
| Hydrochloric Acid SCHEMBL29508527 | 0.99 | IL1B (0.98) | IL1BTNFNLRP3 | |
| Hydrochloric Acid SCHEMBL29508561 | 0.99 | IL1B (0.98) | IL1BTNFNLRP3 | |
| Hydrochloric Acid SCHEMBL29508548 | 0.99 | IL1B (0.98) | IL1BTNFNLRP3 | |
| SCHEMBL22655002 | 0.91 | IL1B (1.00) | IL1BTNFNLRP3 | |
| SCHEMBL22654903 | 0.90 | IL1B (1.00) | IL1BTNFNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969441-A1 | NLRP3 INFLAMMASOME INHIBITORS | Novartis AG (CH) | 2022-03-23 | — | — | EP | claimed |