Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22655066 | 1.00 | LPL (0.34) | LPLLIPGEGFRALDH1A1HPGD | |
| SCHEMBL29276139 | 0.88 | LPL (0.39) | LPLLIPGEGFR | |
| SCHEMBL29508529 | 0.83 | TSHR (0.41) | LPLLIPGALDH1A1HPGDTSHR | |
| SCHEMBL22654957 | 0.83 | TSHR (0.41) | LPLLIPGALDH1A1HPGDTSHR | |
| SCHEMBL28569437 | 0.83 | LPL (0.40) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL29276197 | 0.81 | LPL (0.35) | LPLLIPGEGFR | |
| SCHEMBL30916355 | 0.81 | HIF1A (0.32) | ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL31042939 | 0.80 | LPL (0.34) | LPLLIPGEGFRALDH1A1TSHR | |
| SCHEMBL22655000 | 0.80 | CXCR2 (0.31) | — | |
| SCHEMBL29508580 | 0.80 | CXCR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969441-A1 | NLRP3 INFLAMMASOME INHIBITORS | Novartis AG (CH) | 2022-03-23 | — | — | EP | disclosed |