SCHEMBL29510312

SCHEMBL29510312

CC(C)CC1=CCC(C(=O)O)C(C)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
BCL2L1 Q07817 2/20 0.37
MCL1 Q07820 2/20 0.37
POLB P06746 4/20 0.35
CASP6 P55212 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 3/20 0.34
ALDH1A1 P00352 2/20 0.34
GRM2 Q14416 1/20 0.34
GRM3 Q14832 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.31
FNTA P49354 1/20 0.31
PGGT1B P53609 1/20 0.31
PTGS1 P23219 3/20 0.31
PTGS2 P35354 3/20 0.31
CYP2C9 P11712 2/20 0.31
AKR1C3 P42330 2/20 0.31
CXCR1 P25024 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29980778 0.88 MEN1 (0.55) MEN1KMT2ABCL2L1MCL1POLB
SCHEMBL29510216 0.77
SCHEMBL622514 0.73 ALDH1A1 (0.34) ALDH1A1FNTAPGGT1B
SCHEMBL938459 0.71 POLB (0.51) MEN1KMT2ABCL2L1MCL1POLB
SCHEMBL15450093 0.71 POLB (0.51) MEN1KMT2ABCL2L1MCL1POLB
SCHEMBL938457 0.71 POLB (0.51) MEN1KMT2ABCL2L1MCL1POLB
SCHEMBL938541 0.71 POLB (0.51) MEN1KMT2ABCL2L1MCL1POLB
SCHEMBL938542 0.71 POLB (0.51) MEN1KMT2ABCL2L1MCL1POLB
SCHEMBL1441411 0.71 POLB (0.51) MEN1KMT2ABCL2L1MCL1POLB
SCHEMBL14605795 0.70 POLB (0.37) MEN1KMT2ABCL2L1MCL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3807241-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-04-13 EP disclosed