SCHEMBL29511100

SCHEMBL29511100

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CCCNC(=O)[C@@H](N)CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.51
▸ MC4R P32245 5/20 0.51
▸ PRKACB P22694 1/20 0.47
▸ BMP1 P13497 1/20 0.47
▸ KISS1R Q969F8 1/20 0.47
▸ NPBWR1 P48145 1/20 0.47
▸ OPRM1 P35372 1/20 0.46
▸ OPRD1 P41143 1/20 0.46
▸ OPRK1 P41145 1/20 0.46
▸ OPRL1 P41146 1/20 0.46
▸ CTSL P07711 1/20 0.46
▸ CTSH P09668 1/20 0.46
▸ CTSS P25774 1/20 0.46
▸ CTSK P43235 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511006 0.94 C5AR1 (0.52) C5AR1MC4RKISS1RNPBWR1OPRD1
SCHEMBL29476562 0.94 MC4R (0.50) C5AR1MC4RKISS1R
SCHEMBL29476617 0.94 MC4R (0.50) C5AR1MC4RKISS1R
SCHEMBL31140220 0.93 C5AR1 (0.53) C5AR1MC4RNPBWR1CTSLCTSH
SCHEMBL30264772 0.93 C5AR1 (0.51) C5AR1MC4RKISS1RCTSLCTSH
SCHEMBL29511062 0.92 MC4R (0.51) C5AR1MC4RKISS1RCTSLCTSH
SCHEMBL29511047 0.92 C5AR1 (0.50) C5AR1MC4R
SCHEMBL31620055 0.91 MC4R (0.53) C5AR1MC4RPRKACBNPBWR1OPRM1
SCHEMBL31140228 0.91 C5AR1 (0.50) C5AR1MC4RPRKACBKISS1RNPBWR1
SCHEMBL30510423 0.91 TUBB4A (0.52) C5AR1MC4RKISS1RCTSLCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R C5AR1 72/4885MC4R 4/4885PRKACB 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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