Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29512845 | 0.82 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512759 | 0.81 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512614 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL29512807 | 0.74 | ALDH1A1 (0.64) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512678 | 0.73 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512658 | 0.72 | CYP2C9 (0.57) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512722 | 0.70 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512613 | 0.70 | ALDH1A1 (0.58) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512788 | 0.68 | CUL4A (0.51) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL29512590 | 0.66 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076383-A1 | SULFONANILIDE AND BENZYLSULFONYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2022-04-14 | — | — | WO | disclosed |