Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 11/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20107621 | 1.00 | RORC (0.44) | RORCDHODHSLC6A9SLC6A5 | |
| SCHEMBL28823359 | 1.00 | RORC (0.44) | RORCDHODHSLC6A9SLC6A5 | |
| SCHEMBL20107592 | 0.87 | RORC (0.42) | RORCDHODHSLC6A9 | |
| SCHEMBL21853435 | 0.87 | RORC (0.42) | RORCDHODHSLC6A9 | |
| SCHEMBL29512881 | 0.87 | RORC (0.42) | RORCDHODHSLC6A9 | |
| SCHEMBL30014395 | 0.84 | NR4A2 (0.45) | RORCDHODH | |
| SCHEMBL29816317 | 0.81 | MEN1 (0.35) | — | |
| SCHEMBL20107853 | 0.81 | MEN1 (0.35) | — | |
| SCHEMBL21435678 | 0.79 | DHODH (0.43) | RORCDHODH | |
| SCHEMBL20107634 | 0.79 | DHODH (0.43) | RORCDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-110248937-B | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-03-29 | — | — | CN | disclosed |