Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MDH2 | P40926 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22608624 | 1.00 | MRGPRX4 (0.44) | MRGPRX4KDM4EALDH1A1LMNAHAO1 | |
| SCHEMBL22816228 | 0.93 | MRGPRX4 (0.49) | MRGPRX4KDM4EALDH1A1LMNAHAO1 | |
| SCHEMBL30631919 | 0.93 | MRGPRX4 (0.49) | MRGPRX4KDM4EALDH1A1LMNAHAO1 | |
| Trifluoroacetic Acid SCHEMBL22608719 | 0.91 | HAO1 (0.39) | MRGPRX4HAO1KMO | |
| Trifluoroacetic Acid SCHEMBL22608285 | 0.87 | HAO1 (0.40) | MRGPRX4KDM4EALDH1A1HAO1 | |
| Trifluoroacetic Acid SCHEMBL29490748 | 0.87 | HAO1 (0.40) | MRGPRX4KDM4EALDH1A1HAO1 | |
| SCHEMBL22608628 | 0.84 | MRGPRX4 (0.37) | MRGPRX4KDM4EALDH1A1LMNAHRH3 | |
| SCHEMBL30631925 | 0.84 | KMO (0.43) | MRGPRX4HAO1KMOMAPT | |
| SCHEMBL22816014 | 0.84 | KMO (0.43) | MRGPRX4HAO1KMOMAPT | |
| SCHEMBL22815642 | 0.79 | HAO1 (0.44) | MRGPRX4KDM4EALDH1A1HAO1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114258390-A | Glycolate oxidase inhibitors for disease treatment | 生物马林药物股份有限公司 | 2022-03-29 | — | — | CN | disclosed |