SCHEMBL29514743

SCHEMBL29514743

COc1cc(-n2nc3ccc(C(=O)O)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RARG P13631 3/20 0.40
RARB P10826 2/20 0.40
RARA P10276 2/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALPG P10696 1/20 0.38
RXRA P19793 1/20 0.37
THRB P10828 1/20 0.37
LMNA P02545 1/20 0.36
HCAR3 P49019 2/20 0.36
TDP1 Q9NUW8 1/20 0.35
HTT P42858 1/20 0.35
CHEK2 O96017 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21956098 1.00 CA1 (0.44) CA1CA2HPGDTSHRNPSR1
SCHEMBL21956092 0.90 CA1 (0.43) CA1CA2KDM4ELMNAHTT
SCHEMBL21956097 0.87 MAPT (0.45) CA1CA2LMNATDP1
SCHEMBL4578446 0.85 NPC1 (0.44) CA2HPGDRARGRARBRARA
SCHEMBL1547141 0.85 RXRA (0.40) RARGRARBRARAHSP90AA1RXRA
SCHEMBL21956096 0.83 ESR1 (0.42)
SCHEMBL28547709 0.83 CA1 (0.54) CA1CA2HPGDHSD17B10KDM4E
SCHEMBL12199840 0.82 CA1 (0.48) CA1CA2KDM4EHTTATM
SCHEMBL28823002 0.82 CA1 (0.48) CA1CA2HPGDHSD17B10KDM4E
SCHEMBL28344506 0.82 POLB (0.37) CA1CA2HPGDTSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110546141-B Benzotriazole derivative compound 希普洛化成股份有限公司 2023-03-28 CN disclosed
CN-110546172-B Ultraviolet absorbing coating material and film coated with the same 新中村化学工业株式会社 2022-04-15 CN disclosed