SCHEMBL29592683

SCHEMBL29592683

CCc1nc(N)c2[nH]cnc2n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDPK1 O15530 1/20 0.59
▸ GDA Q9Y2T3 1/20 0.59
▸ PI4KA P42356 2/20 0.47
▸ PI4K2B Q8TCG2 2/20 0.47
▸ PI4K2A Q9BTU6 2/20 0.47
▸ PI4KB Q9UBF8 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ DRD3 P35462 1/20 0.47
▸ XDH P47989 1/20 0.47
▸ LRRK2 Q5S007 1/20 0.47
▸ CDK1 P06493 9/20 0.46
▸ CCNB1 P14635 9/20 0.46
▸ CDK2 P24941 9/20 0.46
▸ CCNA2 P20248 8/20 0.46
▸ CCNA1 P78396 8/20 0.46
▸ POLA1 P09884 1/20 0.46
▸ PIN1 Q13526 1/20 0.45
▸ MAP3K5 Q99683 1/20 0.44
▸ DPP4 P27487 1/20 0.43
▸ PNP P00491 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1924592 1.00 PDPK1 (0.59) PDPK1GDAPI4KAPI4K2BPI4K2A
Water SCHEMBL28083708 0.98 PDPK1 (0.58) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL29514836 0.86 PDPK1 (0.56) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL215054 0.86 PDPK1 (0.56) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL11222102 0.85 PDPK1 (0.63) PDPK1GDAPI4KAPI4K2BPI4K2A
Barbital SCHEMBL2130352 0.85 PDPK1 (0.44) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL17060283 0.84 PDPK1 (0.61) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL1074970 0.83 POLA1 (0.57) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL28299226 0.82 POLA1 (0.53) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL9176120 0.82 PDPK1 (0.59) PDPK1GDAPI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235807-A1 COMPOSITIONS AND METHODS TO IMPROVE GRAFT SURVIVAL SOLID BIOSCIENCES, INC. (US) 2025-11-13 — — WO disclosed
WO-2025235404-A1 FORMULATION FOR GENE THERAPY VECTORS SOLID BIOSCIENCES, INC. (US) 2025-11-13 — — WO disclosed
EP-4622983-A1 METHOD OF SYNTHESIZING 4'-PHOSPHATE ANALOG NUCLEOTIDE PHOSPHORAMIDITE Eli Lilly and Company (US) 2025-10-01 — — EP disclosed
EP-4622982-A1 METHODS OF SYNTHESIZING A TARGETING LIGAND-CONJUGATED NUCLEOTIDE PHOSPHORAMIDITE Eli Lilly and Company (US) 2025-10-01 — — EP disclosed
EP-4558641-A1 METHODS FOR DETECTION AND REDUCTION OF SAMPLE PREPARATION-INDUCED METHYLATION ARTIFACTS Guardant Health, Inc. (US) 2025-05-28 — — EP disclosed
EP-4555090-A1 REGULATORY SYSTEM FOR EXPRESSION OF A GENE OF INTEREST IN A TARGET CELL AND METHOD OF USE THEREOF Icahn School of Medicine at Mount Sinai (US) 2025-05-21 — — EP disclosed
WO-2025085519-A1 R2 RETROTRANSPOSONS FOR GENE WRITING TYPEWRITER THERAPEUTICS, INC. (US) 2025-04-24 — — WO disclosed
EP-4504959-A1 SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS Twist Bioscience Corporation (US) 2025-02-12 — — EP disclosed
EP-4457364-A1 METHODS OF NUCLEIC ACID SEQUENCING USING SURFACE-BOUND PRIMERS Illumina, Inc. (US) 2024-11-06 — — EP disclosed
EP-4409029-A1 POLYNUCLEOTIDE SEQUENCING Illumina, Inc. (US) 2024-08-07 — — EP disclosed
WO-2024015729-A1 REGULATORY SYSTEM FOR EXPRESSION OF A GENE OF INTEREST IN A TARGET CELL AND METHOD OF USE THEREOF ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2024-01-18 — — WO disclosed
WO-2023201046-A1 COMPOSITIONS AND METHOD FOR THE TREATMENT OF X-LINKED DYSTONIA PARKINSONISM LIEBER INSTITUTE, INC. (US) 2023-10-19 — — WO disclosed
WO-2023196499-A1 SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS Twist Bioscience Corporation (US) 2023-10-12 — — WO disclosed
EP-4247968-A1 USE OF DEXTRAMER IN SINGLE CELL ANALYSIS Becton, Dickinson and Company (US) 2023-09-27 — — EP disclosed
WO-2023164437-A1 METHODS FOR TREATING CANCER PATIENTS WITH HOMOLOGOUS RECOMBINATION DEFICIENCY BASED ON TEMPLATED INSERTIONS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2023-08-31 — — WO disclosed
EP-4229210-A1 METHODS OF SYNTHESIZING OLIGONUCLEOTIDES USING TETHERED NUCLEOTIDES Twist Bioscience Corporation (US) 2023-08-23 — — EP disclosed
WO-2023126457-A1 METHODS OF NUCLEIC ACID SEQUENCING USING SURFACE-BOUND PRIMERS ILLUMINA CAMBRIDGE LTD. (GB) 2023-07-06 — — WO disclosed
WO-2023052427-A1 POLYNUCLEOTIDE SEQUENCING ILLUMINA CAMBRIDGE LIMITED (GB) 2023-04-06 — — WO disclosed
WO-2022109339-A1 USE OF DEXTRAMER IN SINGLE CELL ANALYSIS BECTON, DICKINSON AND COMPANY (US) 2022-05-27 — — WO disclosed
WO-2022086866-A1 METHODS OF SYNTHESIZING OLIGONUCLEOTIDES USING TETHERED NUCLEOTIDES Twist Bioscience Corporation (US) 2022-04-28 — — WO disclosed
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