Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FURIN | P09958 | 9/20 | 0.45 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035812 | 0.87 | FURIN (0.52) | SMN1; SMN2FURINPCSK6SIRT6SIRT1 | |
| SCHEMBL29577402 | 0.87 | FURIN (0.52) | SMN1; SMN2FURINPCSK6SIRT6SIRT1 | |
| SCHEMBL29400666 | 0.83 | FURIN (0.49) | FURINPCSK6SIRT6SIRT1 | |
| SCHEMBL13811923 | 0.81 | SIRT6 (0.52) | FURINPCSK6SIRT6SIRT1 | |
| SCHEMBL29514800 | 0.81 | GNPAT (0.52) | FURINPCSK6SIRT6SIRT1CASP1 | |
| SCHEMBL29514754 | 0.81 | GNPAT (0.52) | FURINPCSK6SIRT6SIRT1CASP1 | |
| SCHEMBL29514843 | 0.81 | GNPAT (0.52) | FURINPCSK6SIRT6SIRT1CASP1 | |
| SCHEMBL29514694 | 0.80 | FURIN (0.49) | FURINPCSK6CASP1 | |
| SCHEMBL9495080 | 0.78 | FURIN (0.45) | FURINPCSK6SIRT6SIRT1 | |
| SCHEMBL9495059 | 0.78 | FURIN (0.45) | FURINPCSK6SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621318-A | Peptide therapy for inflammation and fibrosis | 加利福尼亚大学董事会 | 2022-06-14 | — | — | CN | disclosed |
| CN-107531752-B | Peptide therapy for inflammation and fibrosis | 加利福尼亚大学董事会 | 2022-05-10 | — | — | CN | disclosed |
| CN-114181281-A | Peptide therapy for inflammation and fibrosis | 加利福尼亚大学董事会 | 2022-03-15 | — | — | CN | disclosed |