Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 10/20 | 0.41 |
| ▸ | CDK4 | P11802 | 5/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322202 | 1.00 | CCND1 (0.41) | CCND1CDK4CDK6SMN1; SMN2 | |
| SCHEMBL24322358 | 0.81 | CCND1 (0.57) | CCND1CDK4CDK6SMN1; SMN2 | |
| SCHEMBL25695110 | 0.77 | MAPK8 (0.38) | CCND1CDK4 | |
| SCHEMBL24322930 | 0.76 | CCND1 (0.46) | CCND1CDK4CDK6SMN1; SMN2 | |
| SCHEMBL24322292 | 0.70 | CCND1 (0.36) | CCND1CDK4CDK6 | |
| SCHEMBL31373078 | 0.70 | CCND1 (0.47) | CCND1CDK4CDK6 | |
| SCHEMBL29514966 | 0.70 | CCND1 (0.36) | CCND1CDK4CDK6 | |
| SCHEMBL31373079 | 0.70 | CCND1 (0.47) | CCND1CDK4CDK6 | |
| SCHEMBL24323632 | 0.69 | CCND1 (0.51) | CCND1CDK4CDK6 | |
| SCHEMBL29515017 | 0.69 | CCND1 (0.51) | CCND1CDK4CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | disclosed |
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |