Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 7/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.51 |
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24323632 | 1.00 | CCND1 (0.51) | CCND1CDK6CDK4 | |
| SCHEMBL25695270 | 0.78 | CCND1 (0.41) | CCND1CDK6CDK4 | |
| SCHEMBL24322358 | 0.73 | CCND1 (0.57) | CCND1CDK6CDK4 | |
| SCHEMBL24322930 | 0.72 | CCND1 (0.46) | CCND1CDK6CDK4 | |
| SCHEMBL29514922 | 0.69 | CCND1 (0.42) | CCND1CDK6CDK4 | |
| SCHEMBL24322278 | 0.69 | CCND1 (0.42) | CCND1CDK6CDK4 | |
| SCHEMBL29514933 | 0.69 | CCND1 (0.41) | CCND1CDK6CDK4 | |
| SCHEMBL24322202 | 0.69 | CCND1 (0.41) | CCND1CDK6CDK4 | |
| SCHEMBL30541555 | 0.68 | CCND1 (0.54) | CCND1CDK6CDK4 | |
| SCHEMBL24322989 | 0.68 | CCND1 (0.54) | CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | disclosed |
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |